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. 2023 Nov 27;21:452. doi: 10.1186/s12951-023-02110-y

Fig. 8.

Fig. 8

Exosomal miR-210-5p conditions JAK1 by directly targeting the 3′-UTR. A Predicted target genes of miR-210-5p. B qRT-PCR to verify the expression of target genes. C miR-210-5p regulates JAK1 by directly targeting the 3′UTR region. D Luciferase reporter assay confirmed that JAK1 is a target gene of miR-210-5p. E GO enrichment analysis of miR-210-5p target genes. F, G Western blot analysis of downstream target gene expression after miRNA overexpression and knockdown