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[Preprint]. 2023 Nov 16:2023.11.15.567132. [Version 1] doi: 10.1101/2023.11.15.567132

Figure 4. Monocyte/macrophage kinetics in BAL and blood following SARS-CoV-2 infection of SIV+ and SIV naïve PTM.

Figure 4.

A. Representative flow cytometry dot plots of pulmonary infiltrating myeloid cells and lymphocytes in the lungs of two SIV+ PTM before and 2, 7, 21, 28, and 42 days after SARS-CoV-2 exposure. Gated on Time>Live>Single cells>CD45+>SSC-A vs FSC-A. B-E, F-I. Frequencies of Classical (CD45+ HLA-DR+ CD14+ CD16−) (B,F) intermediate (CD45+ HLA-DR+ CD14+ CD16+) (C,G), and non-classical monocytes (CD45+ HLA-DR+ CD14− CD16+) ((D,H) in BAL (B-D) and blood (F-H) before and after SARS-CoV-2 infection. Day 0 = day of SARS-CoV-2 infection. E,I. Activated Classical Monocytes (CD169+) in BAL and blood. Figures B-I: SIVmac239/SARS-CoV-2 infected PTM (blue), and SARS-CoV-2 only infected PTM (orange).