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[Preprint]. 2023 Nov 16:2023.11.15.567132. [Version 1] doi: 10.1101/2023.11.15.567132

Figure 8. Single-cell classification and dynamics of bronchoalveolar lavage cell populations during SIV/SARS-CoV-2 coinfection.

Figure 8.

A. UMAP plots illustrating scRNAseq data obtained from BAL sampling of PTMs (NV18 and NV19) coinfected with SIV and SARS-CoV-2. B. Gene markers utilized for cell type identification. Dot color represents relative gene expression (Rel. Expression), while dot size indicates the proportion of cells expressing the gene (% Expression). Refer to supplemental figure 6 for additional genes used. C-D. Immune cell dynamics in BAL during SARS-CoV-2 infection for the more immunocompromised animal, NV18, (C) and NV19 (D). The baseline (BL) sample was collected prior to SARS-CoV-2 exposure at 48 weeks post-SIV infection.

MC = Mast cells, pDC = plasmacytoid dendritic cells, mDC = myeloid dendritic cells, NK = natural killer cells