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[Preprint]. 2023 Dec 12:2023.11.17.567619. Originally published 2023 Nov 18. [Version 2] doi: 10.1101/2023.11.17.567619

Figure 5. Nipah virus V protein prevents ISG15 induction by HIV-1.

Figure 5.

A-B, Nipah virus V protein was expressed from a lentivector in dendritic cells (A), or macrophages (B), and cells were subsequently transduced with HIV-1-GFP for three days. The percentage of ISG15+ cells was quantified by flow cytometry, and normalized to the values for cells expressing the empty vector. (mean ± SEM, n=4 donors for each). P values were determined by two-tailed, paired t-test. C-D, Nipah virus V protein was expressed in macrophages and subsequently either infected with EMCV (C) or Sendai virus (D). The percentage of ISG15+ cells was measured by flow cytometry, and normalized to the values for cells expressing the empty vector (mean ± SEM, n=3 donors for each). P values were determined by two-tailed, paired t-test.