Table 2.
Hormone responses
| No-Stress | Stress | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hypophagic MDD | Hyperphagic MDD | Within Subjects (T0-T105) | Between Subjects | Hypophagic MDD | Hyperphagic MDD* | Within Subjects (T0-T105) | Between Subjects | |||||||
| Timepoint | M (SD) | M (SD) | Hypophagic MDD | Hyperphagic MDD | p-value | z-value | M (SD) | M (SD) | Hypophagic MDD | Hyperphagic MDD* | p-value | z-value | ||
| Cortisol (µg/dL) | T0 | 15.1 (4.8) | 14.8 (6.9) | 17.8 (7.9) | 13.6 (6.5) | |||||||||
| T105 | 10.6 (4.9) | 10.4 (5.9) | 13.1 (4.7) | 10.2 (4.7) | ||||||||||
| log2 Cortisol | T0 | 3.8 (0.5) | 3.8 (0.6) | z= −2.71 p = 0.006a | z= −2.24 p = 0.025a | 0.500b | −0.688 | 4.0 (0.7) | 3.7 (0.6) | z=−2.06 p = 0.039a | z=−1.35 p = 0.176 | 0.183b | −1.35 | |
| T105 | 3.2 (0.9) | 3.2 (0.7) | 0.804b | −0.254 | 3.6 (0.7) | 3.2 (0.7) | 0.115b | −1.59 | ||||||
| Ghrelin (pg/mL) | T0 | 782.7 (771.7) | 420.6 (195.8) | 671.7 (542.7) | 392.8 (107.1) | |||||||||
| T105 | 654.6 (710.0) | 368.3 (117.9) | 595.3 (479.7) | 332.9 (116.9) | ||||||||||
| log2 Ghrelin | T0 | 9.1 (1.2) | 8.5 (0.9) | z=−1.78 p = 0.075a | z=−0.42 p = 0.674a | 0.238b | −1.23 | 9.1 (1.0) | 8.6 (0.4) | z=−1.22 p = 0.221a | z=−1.26 p = 0.208 | 0.161b | −1.45 | |
| T105 | 8.9 (1.1) | 8.5 (0.5) | 0.210b | −1.30 | 8.9 (1.0) | 8.3 (0.5) | 0.140b | −1.52 | ||||||
M = mean
SD = standard deviation
a
= nonparametric result from the Wilcoxon Signed Ranks test
b
= nonparametric result from the Mann-Whitney U test
*
n = 7 due to data loss of one subject.