Skip to main content
[Preprint]. 2023 Nov 17:rs.3.rs-3471275. [Version 1] doi: 10.21203/rs.3.rs-3471275/v1

Figure 5. Regulon of the human bipolar cell types.

Figure 5.

A. Heatmap showing the identified regulons where the gene expression level (color scale) of transcription factors and the enrichment (dot size) of TF motifs in the snATAC peaks are highly correlated. The rows represent BC cell types, and the columns represent the identified regulons. B. Jaccard heatmap showing the intersection of target regions of the identified TFs. Each cell in the heatmap represents the Jaccard index of target regions between a pair of TFs. C. Jaccard heatmap showing the intersection of target genes of the identified TFs. Each cell in the heatmap represents the Jaccard index of target genes between a pair of TFs. D. Network plot showing the regulons and interactions between them in DB3a, DB3b, BB and GB. Each regulon includes the TF, target regions and target genes. E. ROC-AUC of logistic regression model and SVM model to predict BC cell type based on the accessibility of target regions of identified TFs. F. Heatmap showing the correlation in target-regions-based AUC of the identified regulons.