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[Preprint]. 2023 Nov 17:rs.3.rs-3471275. [Version 1] doi: 10.21203/rs.3.rs-3471275/v1

Figure 6. Differential gene expression associated with sex and age.

Figure 6.

A. Heatmap showing gene expression level of differentially expressed genes (DEGs) during aging in Rod identified with linear mixed effect model (LMM). B. UpSet plot showing the number of cell type specific and common DEGs across major retinal cell classes. C. The number of DEGs identified through sliding window analysis at each age stage. D. The selected KEGG pathways significantly enriched (FDR <0.1) of DEGs during aging identified by LMM across retinal cell classes. E. The examples of DEG during aging involved in the enriched KEGG pathways. F. The number of DEGs between male and female across major retinal cell classes. G. The selected GO terms significantly enriched (FDR < 0.1) of DEGs between male and female across retinal cell classes. H. The selected KEGG pathways significantly enriched (FDR < 0.1) of DEGs with gender dependent aging effect. I. The examples of DEGs with gender dependent aging effect involved in the enriched KEGG pathways.