Table 1.
Summary of fine-mapped GWAS loci associated with the seven GWAS traits.
| AMD | Myopia | POAG | Diabetic retinopathy | ONL thickness | IST thickness | OST thickness | |
|---|---|---|---|---|---|---|---|
| Number of fine-mapped genes | 56 | 391 | 74 | 3 | 81 | 25 | 61 |
| Overlapped with eQTLs | 8 | 67 | 11 | 0 | 23 | 8 | 13 |
| Examples | APOE C2 C3 CRB1 RDH5 TGFBR1 |
PAX6 PDE6G RDH5 TGFBR1 TOMM40 KCNA4 LHX3 |
TFAP2B PLEKHA7 EFEMP1 THSD7A TMCO1 CLIC5 SIX6 |
ABCF1 MIR4640 DDR1 |
ATOH7 MAPT PAX6 RAX RBP3 RDH5 VSX2 |
CNGB3 VSX2 RP1L1 |
MKKS FSCN2 PDE6G PRPH2 RDH5 RHO RP1L1 SAG RLBP1 |