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. 2023 Nov 27;18(11):e0294779. doi: 10.1371/journal.pone.0294779

Fig 2. U-shaped association between serum TGmax levels and mortality among septic patients.

Fig 2

A. Lowess smoothing technique revealed that the lowest 28-day mortality (12.22%) was associated with TGmax levels of 400–500 mg/dL. B. Lowess smoothing technique revealed that the lowest ICU mortality (10.00%) was associated with TGmax levels of 400–500 mg/dL. C. Lowess smoothing technique revealed that the lowest hospital mortality (13.33%) was associated with a TGmax level of 400–500 mg/dL. D. Restricted cubic splines revealed that the relationship between serum TGmax level and risk of 28-day mortality was significantly nonlinear (p = 0.039), resulting in a U-shaped association. The lowest hospital mortality (HR: 0.78, 95% CI: 0.61, 0.99; p <0.05) was associated with a TGmax level of 396.5 mg/dL. E. Restricted cubic splines revealed that the relationship between serum TGmax level and risk of ICU mortality was significantly nonlinear (p = 0.002), resulting in a U-shaped association. The lowest ICU mortality (HR: 0.70, 95% CI: 0.53,0.93; p <0.05) was associated with a TGmax level of 459.6 mg/dL. F. Restricted cubic splines revealed that the relationship between serum TGmax levels and the risk of hospital mortality was significantly nonlinear (p = 0.013), resulting in a U-shaped association. The lowest hospital mortality (HR: 0.78, 95% CI: 0.66, 0.99; p <0.05) was associated with a TGmax level of 410.5 mg/dL. TGmax: the maximum value of serum triglyceride; ICU: intensive care unit.