Direct and Indirect effects of serum aldosterone concentrations on coronary artery calcium score via 10mmHg increase in blood pressure
CAC, coronary artery calcium score; CI, confidence interval.
Adjusted for age, sex, CAC at exam 2 or 3, race, education, insurance status, income, smoking status, alcohol intake, physical activity, statin prescription, BMI, LDL, serum sodium, serum potassium, urinary sodium, urinary potassium, plasma renin activity, and time from aldosterone measurement to CAC follow-up. Relative ratio of CAC at follow-up is calculated per 100 pg/ml increase in serum aldosterone concentrations. 200 iterations were performed for bootstrapping to estimate 95% CI.