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. 2023 Nov 13;7:e2300104. doi: 10.1200/CCI.23.00104

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FIG 4. — Online Analysis module on the OSE. (A) Various analysis tasks are provided in the module, including overall survival and event-free survival analysis based on clinical, gene expression, HER2 protein expression, CNV, ctDNA status, and analysis tools on cBioPortal. (B) An example Kaplan-Meier curve for overall survival based on ctDNA status. Users can easily switch to event-free survival using the provided dropdown list and the analysis plot will be refreshed in real time. To caution users against p-hacking, an alert message is provided with the survival analysis tool. (C) The analysis tools provided through a local instance of cBioPortal platform. CNV, copy-number variation; ctDNA, circulating tumor DNA; HER2, human epidermal growth factor receptor 2; OSE, Osteosarcoma Explorer; TARGET, Therapeutically Applicable Research to Generate Effective Treatments.