Table 3.
Results of the sensitivity analysis for the difference of PAPP-A between women with and without PAS.
| Study excluded | MD (95% CI) | I2 | P |
|---|---|---|---|
| Desai, 2014[17] | 0.40 [0.28, 0.53] | 21% | <.001 |
| Thompson, 2015[19] | 0.46 [0.31, 0.60] | 35% | <.001 |
| Lyell, 2015[18] | 0.42 [0.26, 0.57] | 38% | <.001 |
| Büke, 2018[20] | 0.44 [0.30, 0.58] | 41% | <.001 |
| Penzhoyan, 2019[21] | 0.46 [0.32, 0.59] | 33% | <.001 |
| Borovkov, 2020[22] | 0.40 [0.28, 0.52] | 16% | <.001 |
| Wang, 2021[23] | 0.44 [0.29, 0.58] | 42% | <.001 |
| Wu, 2022[24] | 0.47 [0.34, 0.60] | 22% | <.001 |
CI = confidence interval, MD = mean difference, PAPP-A = pregnancy-associated plasma protein A, PAS = placenta accreta spectrum.