Table 3.

Topological parameters of the top 20 potential targets.

Gene	Degree	Betweenness centrality	Closeness centrality
SRC	114	0.123725382	0.430577223
TP53	94	0.167040116	0.438095238
PIK3R1	92	0.040949213	0.392603129
MAPK3	84	0.046200836	0.410714286
PIK3CA	82	0.033117323	0.399421129
MAPK1	78	0.040145784	0.408888889
RELA	76	0.074611633	0.426584235
AKT1	68	0.042537451	0.404099561
ESR1	66	0.105096604	0.417549168
CREBBP	64	0.091422084	0.404692082
PTPN11	60	0.012160304	0.37704918
VEGFA	56	0.028070465	0.378600823
EGFR	56	0.033644398	0.393723252
MAPK14	54	0.038091535	0.397122302
JAK2	54	0.024503912	0.37398374
HDAC1	44	0.030346039	0.37449118
ITGB1	44	0.021372074	0.357050453
ITGB3	42	0.00594634	0.34543179
MAPK8	42	0.017894412	0.371467026
ITGAV	40	0.005583193	0.340740741