Table 2.

Relative Risk of Incident Tuberculosis Disease in Rifampin-Resistant Multidrug-Resistant Tuberculosis Household Contacts at 1-Year Follow-up

Household Contact Risk Groupa	Relative Risk of Incident TB Disease (95% Confidence Interval)b,c,d	Overall P Value
Age <5 y	11.5 (1.7–78.7)	.0015
Diagnosed with human immunodeficiency virus	10.4 (2.4–45.6)
TB infection-positive	2.9 (.5, 17.8)
Not high-risk	Reference group

Abbreviation: TB, tuberculosis.

High-risk defined as age <5 years (regardless of human immunodeficiency virus (HIV) and TB infection (TBI) status); age ≥5 years and diagnosed with HIV (regardless of TBI status); or age ≥5 years, not diagnosed with HIV/unknown and TBI-positive at entry via tuberculin skin test or interferon-gamma release assay.

Log-binominal regression fitted using generalized estimating equations to account for clustering within households. Relative risks use household contacts who were categorized as not high-risk as the reference group.

TB disease includes confirmed, possible, and probable TB disease.

Wald 95% confidence interval, estimated using empirical standard errors.