Figure 1.

Examples of FLAIR and T2w MRI and H&E slides for 3 cases. The last preoperative MRI is shown with an earlier reference MRI used to assess the growth pattern. Recurrent lesions are outlined with a rectangle. Examples of microcysts are indicated by a “†” symbol. (A) Recurrent tumor with mismatch sign; preoperative MRI shows pre-existing treatment effect, but recurrent growth is mismatched with hyperintense rim; growth pattern is mostly expansive; H&E does not show microcysts. (B) Recurrent tumor that is partly mismatched, so this case shows a T2-FLAIR mismatch area but no mismatch sign; growth pattern is mixed; H&E shows large microcysts. Note that the source of the histopathology (mismatch area or not) is unknown. (C) Recurrent tumor without T2-FLAIR mismatch; growth pattern is mostly invasive; H&E shows no microcysts.