Table 3:
Toxicities of Induction Chemotherapy
| CTCAE Grade | ||||
|---|---|---|---|---|
| 3 | 4 | 5 | Total | |
| Neutropenia | 2 | 3 | 0 | 5 (9%) |
| Diarrhea | 4 | 0 | 0 | 4 (7%) |
| Nausea | 4 | 0 | 0 | 4 (7%) |
| Vomiting | 3 | 0 | 0 | 3 (5%) |
| Dehydration | 2 | 0 | 0 | 2 (4%) |
| Hypokalemia | 2 | 0 | 0 | 2 (4%) |
| Alanine aminotransferase increased | 1 | 0 | 0 | 1 (2%) |
| Anemia | 1 | 0 | 0 | 1 (2%) |
| Anorexia | 1 | 0 | 0 | 1 (2%) |
| Decreased Glomerular Filtration Rate | 0 | 1 | 0 | 1 (2%) |
| Hand-and-foot syndrome | 1 | 0 | 0 | 1 (2%) |
| Hyponatremia | 1 | 0 | 0 | 1 (2%) |
| Pneumonia | 1 | 0 | 0 | 1 (2%) |
| Intracranial hemorrhage | 0 | 0 | 1 | 1 (2%) |
| Mucositis oral | 1 | 0 | 0 | 1 (2%) |
| Pruritus | 1 | 0 | 0 | 1 (2%) |
| Rash | 1 | 0 | 0 | 1 (2%) |
| Sepsis | 0 | 1 | 0 | 1 (2%) |
| Thrombosis/thrombus/embolism | 1 | 0 | 0 | 1 (2%) |
| Weight loss | 1 | 0 | 0 | 1 (2%) |
| Laryngospasm | 1 | 0 | 0 | 1 (2%) |
| Sudden Cardiac Arrest | 0 | 0 | 1 | 1 (2%) |
Includes all grade 3 or greater toxicities seen during induction chemotherapy and assessed by investigator to be possibly, probably, or definitely due to therapy