Table 5:
Survival Estimates
| Population | No of Patients | KM Estimate | 95% CI |
|---|---|---|---|
|
| |||
| Overall Survival, 3 Year | |||
| Entire Group | 54 | 75% | (61,85) |
| Sub-Group | |||
| T4 | 26 | 72% | (50,86) |
| non T4 | 28 | 75% | (57,89) |
| Upfront Larynx indicated | 11 | 73% | (37,90) |
| Chemoradiaiton indicated | 39 | 78% | (61,88) |
| off protocol | 4 | ||
|
| |||
| Disease Free Survival, 3 Year | |||
| Entire Groupφ | 46 | 59% | (42,72) |
| Sub-Group | |||
| T4 | 22 | 48% | (25,67) |
| non T4 | 24 | 69% | (46,84) |
| Upfront Larynx indicated | 8 | 63% | (23,86) |
| Chemoradiaiton indicated | 37 | 56% | (38,71) |
|
| |||
| Laryngectomy Free Survival, 3 Year | |||
| Entire Group | 54 | 46% | (32, 59) |
| Sub-Group | |||
| T4 | 26 | 44% | (25,62) |
| non T4 | 28 | 48% | (29,66) |
| Chemoradiaiton indicated | 39 | 56% | (39,71) |
φ
DFS defined for only those who received protocol defined treatment. Excludes: 2 early deaths, 2 off protocol during IC for AEs, 5 off protocol after IC completion for patient refusal of protocol defined treatment (3 early salvage refusals opted for CRT, 1 no CRT for performance status decline, and 1 no CRT at UM for follow-up to be treated closer to home).