Table 1. Diagnostic Criteria of TAFRO Syndrome.

Diagnostic criteria	Case 1	Case 2
Major categories
Anasarca	+	+
Thrombocytopenia	+	+
Systemic inflammation	+	+
Minor categories	+	+
Castleman disease-like features on lymph node biopsy	+	+
Reticulin myelofibrosis	+	+
Mild organomegaly	+	+
Progressive renal insufficiency	+	+

A diagnosis of TAFRO syndrome requires all three major categories and at least two of four minor categories. Malignancies, autoimmune disorders, infectious disorders, POEMS syndrome, hepatic cirrhosis, and thrombotic thrombocytopenic purpura/hemolytic uremic syndrome were excluded.