Table 2.

Summary of patient outcome with respect to IKZF1 mutation status.

Outcome	mut. IKZF1	wt-IKZF	OR/HR	p
n/N (%)	45/1606 (2.8)	1561/1606 (96.7)
CR rate, n (%)	23/45 (51.1%)	1112/1606 (69.2)	0.42 [0.23–0.77]	0.004
EFS	1.7 months [1.2–5.0]	7.5 months [6.7–8.2]	1.69 [1.23–2.32]	0.001
RFS	6.1 months [2.6–29.4]	18.4 months [15.8–22.3]	1.75 [1.10–2.80]	0.019
OS	7.5 months [5.1–14.7]	17.8 months [16.1–19.9]	1.74 [1.27–2.40]	0.001

Survival times are displayed in months. Square brackets show 95%-confidence intervals. Boldface indicates statistical significance (p < 0.05).

CR complete remission, EFS event-free survival, HR hazard ratio, Mut. mutated, n/N number, OR odds ratio, OS overall survival, RFS relapse-free-survival, wt wild-type.