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. 2023 Oct 11;37(12):2468–2478. doi: 10.1038/s41375-023-02056-y

Fig. 5. Gene expression analysis of centriolar proteins in PCD patients and their correlation with survival in MM patients.

Fig. 5

A Progression-free survival of 654 MM patients treated in the HD4 and MM5 trials depending on CEP350 mRNA expression levels. Shaded areas indicate 95% CI estimates. B mRNA expression levels of the centriole elongation factor CPAP in CD138pos plasma cells from 10 healthy individuals, 22 patients with MGUS and 331 patients with MM. Gene expression represents log2 of GCRMA normalized data using the 223513_at probe. C Overall survival of 654 MM patients treated in the HD4 and MM5 trials depending on mRNA expression levels of CEP20, a centriolar elongation inhibitor. Shaded areas indicate 95% CI estimates.