Table 2.
Characteristic parameters of target network node of main active ingredients of LEO.
| Gene | Betweenness（BC） | Closeness (CC) | Degree (DC) |
|---|---|---|---|
| STAT3 | 271.2 | 0.7759 | 64 |
| SRC | 252.5 | 0.7627 | 62 |
| MAPK1 | 143.7 | 0.7377 | 58 |
| MAPK3 | 140.9 | 0.7377 | 58 |
| AKT1 | 85.56 | 0.6522 | 42 |
| JUN | 71.85 | 0.6164 | 34 |
| PIK3CA | 66.53 | 0.6618 | 46 |
| STAT5A | 55.95 | 0.6522 | 42 |
| ESR1 | 39.99 | 0.6250 | 36 |
| EGFR | 33.96 | 0.6338 | 38 |
| PTK2 | 32.15 | 0.6000 | 30 |
| PTPN11 | 31.47 | 0.6522 | 42 |
| JAK2 | 24.42 | 0.6250 | 36 |
| JAK1 | 23.85 | 0.6164 | 38 |
| IGF1R | 20.59 | 0.5844 | 26 |
| FYN | 19.57 | 0.6164 | 34 |
| LCK | 19.05 | 0.6338 | 38 |
| MAPK14 | 15.01 | 0.6000 | 30 |
| JAK3 | 12.86 | 0.5921 | 32 |