Table 2.
Phenotype of F2 generation mice.
| F1 generation parental composition (♂ × ♀) | Mating method | Number of hairless phenotypes of F2 generation | Number of normal phenotypes of F2 generation | Phenotype separation ratio (hairless: normal) |
|---|---|---|---|---|
| HL (HL × HL) × NIH (HL × NIH) | Test cross | 41 | 45 | 0.95 |
| HL (HL × HL) × NIH (NIH × HL) | Test cross | 37 | 49 | |
| NIH (HL × NIH) × HL (HL × HL) | Test cross + negative crossing | 24 | 19 | |
| NIH (NIH × HL) × HL (HL × HL) | Test cross + negative crossing | 42 | 38 | |
| NIH (NIH × HL) × NIH (NIH × NIH) | – | 0 | 20 | 0 |
| NIH (NIH × HL) × NIH (NIH × HL) | Self-cross | 17 | 62 | 0.29 |
| NIH (HL × NIH) × NIH (HL × NIH) | Self-cross + negative crossing | 24 | 80 |