Table 1.
Characteristics of the subjects included in the entire present study.
| BNT162b1 vaccine | mRNA-1273 vaccine | |||
|---|---|---|---|---|
| 1st dose | 2nd dose | 1st dose | 2nd dose | |
| N | 3024 | 2554 | 1521 | 1328 |
| Female (%) | 46.30 | 45.97 | 40.30 | 40.44 |
| Age (mean ± SD) | 52.35 ± 11.54 | 53.55 ± 11.49 | 46.00 ± 11.13 | 46.50 ± 11.22 |
| Local reaction (%) | ||||
| Pain in vaccination site | 86.67 | 82.34 | 86.52 | 80.57 |
| Vaccination site becomes red | 10.35 | 13.78 | 33.99 | 37.65 |
| Swelling of vaccination site | 18.78 | 21.34 | 40.37 | 42.02 |
| Vaccination site becomes hard | 11.71 | 11.82 | 21.04 | 19.73 |
| Itching of vaccination site | 8.80 | 11.39 | 26.89 | 26.05 |
| Vaccination site becomes hot | 17.72 | 17.42 | 37.74 | 38.03 |
| Movement disorder (can’t raise the arm) at the vaccination site | 23.54 | 19.73 | 30.18 | 25.53 |
| Internal bleeding in vaccination site | 1.39 | 0.78 | 0.99 | 1.20 |
| There is nothing that applies in this | 7.28 | 9.98 | 4.01 | 8.28 |
| Systemic reaction (%) | ||||
| 37.5 degrees Celsius or higher fever | 6.58 | 36.22 | 17.75 | 83.21 |
| 38 degrees Celsius or higher fever | 1.55 | 15.94 | 5.85 | 58.81 |
| Fatigue | 24.64 | 48.83 | 35.44 | 70.86 |
| Chills (pathological) | 2.55 | 11.47 | 6.44 | 37.12 |
| Hot flash | 4.83 | 8.89 | 7.30 | 15.44 |
| Peripheral coolness (cold of hands and feet) | 0.56 | 1.33 | 0.72 | 4.74 |
| Numbness | 1.65 | 1.53 | 2.76 | 2.48 |
| Shivering | 0.20 | 1.02 | 1.12 | 4.59 |
| Dizzy | 1.72 | 2.98 | 2.10 | 5.72 |
| Headache | 11.57 | 25.29 | 15.71 | 43.37 |
| Sore throat | 0.69 | 0.74 | 0.72 | 1.96 |
| Mouth and throat discomfort | 1.09 | 1.25 | 1.18 | 2.33 |
| Back pain | 1.22 | 4.46 | 2.96 | 9.56 |
| Swelling of lymph nodes (especially neck, armpit, inguinal part) | 0.73 | 2.51 | 2.24 | 1.96 |
| Pain of lymph nodes (especially neck, armpit, inguinal part) | 1.39 | 4.03 | 3.88 | 5.87 |
| Chest pain | 0.73 | 1.10 | 1.25 | 1.20 |
| Stomach ache | 0.76 | 1.21 | 0.79 | 1.81 |
| Abdominal discomfort | 1.22 | 1.41 | 0.79 | 2.11 |
| Eye pain | 0.40 | 0.55 | 0.46 | 1.43 |
| Joint pain | 3.64 | 11.55 | 5.85 | 23.64 |
| Muscle pain | 9.95 | 12.14 | 13.54 | 19.43 |
| Musculoskeletal discomfort (such as muscle tension) | 1.55 | 3.05 | 1.84 | 3.84 |
| Limb pain | 1.06 | 1.92 | 1.05 | 3.16 |
| Limb discomfort | 0.50 | 1.17 | 0.66 | 1.96 |
| Snot | 1.06 | 0.98 | 0.99 | 1.81 |
| Stuffy nose | 0.66 | 0.55 | 0.53 | 1.20 |
| Nausea | 1.65 | 2.47 | 1.97 | 4.52 |
| Vomiting | 0.23 | 0.43 | 0.59 | 1.13 |
| Loss of appetite | 1.16 | 4.50 | 2.70 | 14.83 |
| Diarrhea | 1.92 | 2.70 | 2.17 | 3.46 |
| Loose stool | 0.83 | 1.61 | 0.72 | 1.58 |
| Constipation | 0.23 | 0.39 | 0.33 | 0.23 |
| Cough | 0.60 | 0.43 | 0.59 | 1.58 |
| Sneeze | 0.33 | 0.35 | 0.46 | 0.45 |
| Dyspnea | 0.17 | 0.04 | 0.20 | 0.38 |
| Muscle weakness | 0.33 | 0.67 | 0.13 | 1.36 |
| Stomatitis | 0.40 | 0.63 | 0.26 | 0.98 |
| Urticaria (rash that disappears within a few hours) | 0.36 | 0.63 | 0.33 | 0.60 |
| Eczema (long-term rash) | 0.17 | 0.43 | 0.72 | 0.53 |
| Blunt feeling | 0.50 | 0.51 | 0.85 | 1.43 |
| Sleepy in the daytime | 5.19 | 8.22 | 4.93 | 9.94 |
| Insomnia | 0.43 | 0.82 | 0.66 | 1.28 |
| Hyperhidrosis | 0.43 | 0.74 | 0.33 | 1.28 |
| There is nothing that applies in this | 56.35 | 29.44 | 43.26 | 4.37 |
SD, standard deviation.