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. 2023 Aug 28;30(6):2736–2749. doi: 10.1007/s12350-023-03358-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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PET images representing a patient from the clinical cohort pre- (A, B) and post-motion (C, D) correction. In the polar plot in A, a motion artifact has caused a false positive defect (20.1 %) in the RCA territory. In the post-motion correction polar plot in C, the motion artifact is completely reduced (defect 0.0 %). Splash images of short axis, horizontal long axis, and vertical long axis in B demonstrate the effect of motion artifacts on the visual interpretation of the images. The inferior wall appears hypoperfused compared to the rest of the myocardium. The post-motion correction splash images in D, demonstrate a uniform tracer uptake, thereby eliminating any suspicions of defects in the inferior wall. MBF, myocardial blood flow (mL⋅min⁻¹⋅g⁻¹); PTF, perfusable tissue fraction (mL⋅mL⁻¹)