Table 1.
Differential expression of AHNAKs mRNA in tumor and corresponding non-tumor tissues.
| Cancer Type |
Number of Cases | AHNAK (Exp: Mean ± SD) | AHNAK2 (Exp: Mean ± SD) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Tumor | Normal | Tumor Exp | Normal Exp | logFC | P-Value | Tumor | Normal | logFC | P-Value | |
| ACC | 79 | – | 3.131 ± 0.990 | – | – | – | 0.457 ± 0.605 | – | – | – |
| BLCA | 408 | 19 | 4.983 ± 1.047 | 6.399 ± 0.965 | -1.416 | <0.001* | 1.530 ± 1.420 | 2.565 ± 1.562 | -1.036 | 0.003* |
| BRCA | 1098 | 113 | 6.012 ± 0.948 | 7.603 ± 0.599 | -1.591 | <0.001* | 1.662 ± 0.902 | 1.800 ± 0.530 | -0.137 | 0.002* |
| CESC | 306 | 3 | 5.500 ± 0.879 | 6.517 ± 0.678 | -1.017 | 0.046* | 2.744 ± 1.288 | 2.961 ± 1.037 | -0.217 | 0.830 |
| CHOL | 36 | 9 | 5.058 ± 0.975 | 3.911 ± 0.486 | 1.147 | 0.002* | 1.853 ± 1.448 | 0.069 ± 0.048 | 1.784 | <0.001* |
| COAD | 458 | 41 | 4.419 ± 0.953 | 5.905 ± 0.731 | -1.486 | <0.001* | 1.208 ± 0.870 | 1.558 ± 1.078 | -0.349 | 0.038* |
| DLBC | 48 | – | 3.468 ± 1.196 | – | – | – | 0.139 ± 0.141 | – | – | – |
| ESCA | 162 | 11 | 5.745 ± 0.838 | 6.151 ± 1.049 | -0.406 | 0.185 | 3.326 ± 1.599 | 2.574 ± 2.209 | 0.752 | 0.183 |
| GBM | 167 | 5 | 3.239 ± 0.921 | 3.567 ± 0.508 | -0.329 | 0.441 | 0.878 ± 0.759 | 1.663 ± 0.654 | -0.785 | 0.017* |
| HNSC | 502 | 44 | 6.233 ± 0.878 | 6.751 ± 0.893 | -0.518 | <0.001* | 4.265 ± 1.226 | 3.583 ± 1.185 | 0.683 | <0.001* |
| KICH | 65 | 24 | 5.229 ± 0.718 | 5.543 ± 0.698 | -0.314 | 0.045* | 0.946 ± 0.971 | 0.389 ± 0.497 | 0.557 | 0.027* |
| KIRC | 531 | 72 | 6.066 ± 0.770 | 6.133 ± 0.567 | -0.067 | 0.517 | 2.643 ± 1.151 | 0.474 ± 0.390 | 2.168 | <0.001* |
| KIRP | 289 | 32 | 5.588 ± 0.916 | 5.682 ± 0.470 | -0.094 | 0.861 | 3.020 ± 1.247 | 0.545 ± 0.508 | 2.475 | <0.001* |
| LAML | 151 | – | 6.385 ± 0.991 | – | – | – | 0.627 ± 0.522 | – | – | – |
| LGG | 525 | – | 4.479 ± 0.937 | – | – | – | 0.550 ± 0.537 | – | – | – |
| LIHC | 373 | 50 | 4.171 ± 0.811 | 3.622 ± 0.509 | 0.549 | <0.001* | 0.275 ± 0.558 | 0.075 ± 0.076 | 0.200 | |
| LUAD | 515 | 59 | 4.764 ± 1.115 | 6.835 ± 0.706 | -2.071 | <0.001* | 2.291 ± 1.270 | 1.102 ± 0.509 | 1.189 | <0.001* |
| LUSC | 501 | 49 | 5.327 ± 0.953 | 6.833 ± 0.621 | -1.506 | <0.001* | 2.994 ± 1.441 | 1.202 ± 0.519 | 1.792 | <0.001* |
| MESO | 86 | – | 6.029 ± 0.703 | – | – | – | 2.544 ± 1.177 | – | – | – |
| OV | 379 | – | 4.815 ± 0.877 | – | – | – | 2.106 ± 1.014 | – | – | – |
| PAAD | 178 | 4 | 5.716 ± 0.796 | 5.414 ± 0.306 | 0.302 | 0.132 | 2.973 ± 1.245 | 1.715 ± 0.688 | 1.258 | 0.0300* |
| PCPG | 183 | 3 | 3.610 ± 0.964 | 3.665 ± 0.479 | -0.054 | 0.910 | 0.982 ± 0.946 | 0.080 ± 0.015 | 0.902 | 0.023* |
| PRAD | 496 | 52 | 5.516 ± 0.765 | 5.908 ± 0.748 | -0.392 | <0.001* | 1.095 ± 0.613 | 2.169 ± 0.857 | -1.073 | <0.001* |
| READ | 167 | 10 | 4.251 ± 0.952 | 6.505 ± 0.935 | -2.254 | <0.001* | 1.108 ± 0.802 | 2.401 ± 1.168 | -1.293 | <0.001* |
| SARC | 263 | 2 | 5.642 ± 0.882 | 5.322 ± 0.866 | 0.319 | 0.598 | 2.557 ± 1.373 | 1.956 ± 2.402 | 0.600 | 0.611 |
| SKCM | 471 | 1 | 4.794 ± 1.071 | 5.133 | – | – | 1.836 ± 1.388 | 1.020 | – | – |
| STAD | 375 | 32 | 5.127 ± 0.930 | 6.2 ± 1.052 | -1.073 | <0.001* | 2.100 ± 1.321 | 2.828 ± 1.910 | -0.728 | 0.059 |
| TGCT | 156 | – | 4.212 ± 0.970 | – | – | – | 0.651 ± 0.490 | – | – | – |
| THCA | 510 | 58 | 4.929 ± 0.756 | 5.236 ± 0.617 | -0.307 | 0.001* | 1.901 ± 1.209 | 0.439 ± 0.194 | 1.462 | <0.001* |
| THYM | 119 | 2 | 3.901 ± 1.326 | 5.612 ± 2.351 | -1.711 | 0.173 | 0.447 ± 0.675 | 0.778 ± 0.812 | -0.330 | 0.309 |
| UCEC | 544 | 35 | 4.157 ± 0.868 | 6.439 ± 0.797 | -2.282 | <0.001* | 1.386 ± 1.062 | 2.507 ± 1.011 | -1.121 | <0.001* |
| UCS | 56 | – | 4.041 ± 0.850 | – | – | – | 1.251 ± 0.630 | – | – | – |
| UVM | 80 | – | 4.321 ± 0.709 | – | – | – | 2.673 ± 1.444 | – | – | – |
Exp, expression; SD, Standard Deviation; LogFC, Log2 fold change; -, no applicable datas; *, P-value < 0.05 was considered statistically significant.