Table 3.
Contribution of the expression of AHNAK to survival by univariate Cox regression analysis in cancers.
| Cancer Type | OS | PFS | DFS | DSS | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HR | 95%CI | P | HR | 95%CI | P | HR | 95%CI | P-value | HR | 95%CI | P | |
| ACC | 1.129 | 0.750-1.698 | 0.561 | 1.170 | 0.847-1.617 | 0.341 | 1.210 | 0.636-2.300 | 0.561 | 1.091 | 0.715-1.665 | 0.686 |
| BLCA | 1.380 | 1.180-1.615 | 0.000* | 1.290 | 1.103-1.508 | 0.001* | 0.956 | 0.667-1.371 | 0.807 | 1.442 | 1.188-1.750 | 0.000* |
| BRCA | 0.980 | 0.827-1.160 | 0.812 | 0.941 | 0.793-1.117 | 0.489 | 0.857 | 0.690-1.064 | 0.162 | 0.870 | 0.699-1.082 | 0.211 |
| CESC | 1.335 | 0.997-1.787 | 0.053 | 1.068 | 0.810-1.408 | 0.642 | 0.886 | 0.567-1.383 | 0.593 | 1.278 | 0.918-1.780 | 0.146 |
| CHOL | 0.874 | 0.541-1.411 | 0.582 | 0.953 | 0.601-1.511 | 0.837 | 1.411 | 0.672-2.960 | 0.363 | 0.947 | 0.567-1.583 | 0.836 |
| COAD | 1.049 | 0.844-1.304 | 0.667 | 1.064 | 0.885-1.279 | 0.508 | 1.095 | 0.736-1.630 | 0.653 | 1.058 | 0.819-1.366 | 0.667 |
| DLBC | 1.236 | 0.672-2.275 | 0.495 | 1.280 | 0.763-2.148 | 0.350 | 1.278 | 0.512-3.192 | 0.599 | 1.232 | 0.487-3.115 | 0.659 |
| ESCA | 0.720 | 0.542-0.957 | 0.024* | 0.794 | 0.614-1.027 | 0.079 | 0.940 | 0.569-1.551 | 0.807 | 0.742 | 0.534-1.032 | 0.076 |
| GBM | 1.121 | 0.949-1.325 | 0.179 | 1.113 | 0.930-1.331 | 0.243 | – | – | – | 1.143 | 0.954-1.370 | 0.147 |
| HNSC | 1.036 | 0.879-1.221 | 0.676 | 0.911 | 0.771-1.075 | 0.270 | 0.918 | 0.580-1.453 | 0.716 | 1.011 | 0.817-1.251 | 0.921 |
| KICH | 0.774 | 0.320-1.871 | 0.569 | 0.665 | 0.303-1.458 | 0.309 | 0.697 | 0.151-3.215 | 0.643 | 0.859 | 0.312-2.367 | 0.769 |
| KIRC | 0.757 | 0.641-0.894 | 0.001* | 0.837 | 0.698-1.003 | 0.054 | 1.117 | 0.634-1.969 | 0.702 | 0.708 | 0.579-0.867 | 0.001* |
| KIRP | 0.930 | 0.664-1.302 | 0.672 | 0.690 | 0.530-0.898 | 0.006* | 0.743 | 0.500-1.104 | 0.141 | 0.685 | 0.469-1.001 | 0.051 |
| LAML | 1.142 | 0.926-1.409 | 0.214 | – | – | – | – | – | – | – | – | – |
| LGG | 0.880 | 0.733-1.057 | 0.172 | 0.929 | 0.801-1.079 | 0.335 | 0.978 | 0.618-1.546 | 0.923 | 0.937 | 0.771-1.139 | 0.512 |
| LIHC | 0.966 | 0.777-1.202 | 0.758 | 0.989 | 0.816-1.198 | 0.910 | 0.860 | 0.693-1.068 | 0.172 | 0.939 | 0.707-1.248 | 0.665 |
| LUAD | 1.091 | 0.958-1.242 | 0.190 | 1.042 | 0.922-1.176 | 0.511 | 0.957 | 0.798-1.147 | 0.632 | 1.103 | 0.936-1.301 | 0.241 |
| LUSC | 1.069 | 0.919-1.244 | 0.387 | 1.188 | 0.982-1.437 | 0.077 | 0.946 | 0.714-1.254 | 0.699 | 1.141 | 0.894-1.456 | 0.290 |
| MESO | 1.156 | 0.803-1.665 | 0.436 | 1.097 | 0.755-1.594 | 0.628 | 0.791 | 0.342-1.827 | 0.583 | 1.068 | 0.670-1.701 | 0.783 |
| OV | 1.142 | 0.985-1.324 | 0.079 | 0.957 | 0.837-1.093 | 0.514 | 0.912 | 0.751-1.106 | 0.349 | 1.166 | 0.994-1.367 | 0.059 |
| PAAD | 1.743 | 1.287-2.36 | 0.000* | 1.701 | 1.284-2.252 | 0.000* | 2.870 | 1.409-5.846 | 0.004* | 1.775 | 1.261-2.499 | 0.001* |
| PCPG | 1.006 | 0.489-2.069 | 0.988 | 0.951 | 0.618-1.464 | 0.820 | 1.523 | 0.554-4.186 | 0.414 | 1.178 | 0.504-2.754 | 0.706 |
| PRAD | 0.669 | 0.333-1.341 | 0.257 | 0.779 | 0.602-1.008 | 0.057 | 0.779 | 0.488-1.242 | 0.294 | 0.438 | 0.157-1.220 | 0.114 |
| READ | 0.769 | 0.490-1.209 | 0.255 | 1.004 | 0.685-1.471 | 0.985 | 1.290 | 0.425-3.911 | 0.653 | 0.528 | 0.293-0.951 | 0.034* |
| SARC | 0.758 | 0.594-0.967 | 0.026* | 0.777 | 0.636-0.949 | 0.014* | 0.865 | 0.651-1.148 | 0.316 | 0.654 | 0.499-0.858 | 0.002* |
| SKCM | 0.981 | 0.863-1.114 | 0.763 | 0.955 | 0.858-1.063 | 0.401 | – | – | – | 0.937 | 0.818-1.073 | 0.346 |
| STAD | 1.113 | 0.929-1.333 | 0.244 | 1.105 | 0.910-1.343 | 0.313 | 1.149 | 0.813-1.623 | 0.431 | 1.122 | 0.893-1.411 | 0.324 |
| TGCT | 1.619 | 0.528-4.959 | 0.399 | 1.074 | 0.787-1.464 | 0.654 | 0.971 | 0.695-1.358 | 0.865 | 1.792 | 0.524-6.127 | 0.352 |
| THCA | 1.224 | 0.619-2.421 | 0.561 | 0.908 | 0.639-1.291 | 0.591 | 1.076 | 0.658-1.759 | 0.770 | 0.707 | 0.275-1.817 | 0.472 |
| THYM | 1.019 | 0.617-1.683 | 0.941 | 0.912 | 0.652-1.276 | 0.591 | – | – | – | 0.644 | 0.262-1.583 | 0.338 |
| UCEC | 0.984 | 0.777-1.247 | 0.895 | 0.917 | 0.749-1.124 | 0.405 | 0.846 | 0.628-1.141 | 0.274 | 1.039 | 0.779-1.386 | 0.793 |
| UCS | 0.823 | 0.574-1.180 | 0.289 | 0.773 | 0.542-1.102 | 0.155 | 0.572 | 0.281-1.166 | 0.124 | 0.708 | 0.481-1.043 | 0.081 |
| UVM | 0.686 | 0.344-1.365 | 0.283 | 0.922 | 0.509-1.670 | 0.789 | – | – | – | 0.652 | 0.314-1.353 | 0.251 |
OS, Overall survival, PFS, Progression free survival, DFS, Disease free survival, DSS, Disease specific survival. *, P-value < 0.05 was considered statistically significant.