Table 1.

The diseases prevented by glyceollins and related signaling pathways.

Diseases	Signaling pathways
Breast cancer	Estrogen-receptor dependent and independent pathways
Ovarian cancer	Estrogen-receptor pathway
Prostatic cancer	Estrogen-receptor pathway
Lung cancer	HIF-1α and VEGF signaling pathways
Cardiovascular disease	RhoA pathway
Metabolic syndrome	AMPK and insulin signaling pathways
Neurodegeneration	Nrf2 and NF-κB signaling pathways
Osteoporosis	Estrogen-receptor pathway
Inflammation	Toll-like receptor and HMGB1 signaling pathways
Skin pigmentation	Melanogenesis pathway