Figure 4.

Dornase alfa reduces the formation of adhesions but maintains wound healing

To test various typical clinical scenarios, mice were subjected to anastomosis of the small intestine (A) deserositation (B) and thermal injury (C) Treatment with dornase alfa prevented the formation of adhesions in all three scenarios almost completely. Additionally, it did not affect the rate of incision hernia, suture insufficiency, peritonitis, or mortality but rather improved it. Data shown as mean ± SD. Statistics: Kruskal-Wallis test with Dunn’s correction.