Fig. 1.
Novel applications of multimodality cardiac imaging and biomarkers drive advances in screening for radiation-induced cardiac disease through earlier and more specific recognition of its multiple manifestations, including cardiac fibrosis, valvular heart disease, coronary artery disease, and pericardial disease. CT, computed tomography; MRI, magnetic resonance imaging; PET, positron emission tomography; MPI, myocardial perfusion imaging; TTE, transthoracic echocardiography; GLS, global longitudinal strain; 18F-FDG, fluorine 18 fluorodeoxyglucose; miRNA, micro-ribonucleic acid; PIGF, placental growth factor; Gal-3, galectin-3; MPO, myeloperoxidase; CRP, C-reactive protein; hs, high sensitivity