Table 2.
Summary of EoE-IQ item-level response distribution at baseline and week 24
| Time point/EoE-IQ item | Mean item score (SD) | 95% CI | Frequency (%) | ||||
|---|---|---|---|---|---|---|---|
| Not at all | A little | Somewhat | Quite a bit | Extremely | |||
| Baseline EoE-IQ score (n = 224) | |||||||
| 1. Bothered by symptoms | 3.3 (0.89) | 3.22–3.45 | 1 (0.4) | 41 (18.3) | 84 (37.5) | 78 (34.8) | 20 (8.9) |
| 2. Worried about swallowing | 3.1 (1.09) | 2.98–3.27 | 14 (6.3) | 53 (23.7) | 73 (32.6) | 59 (26.3) | 25 (11.2) |
| 3. Worried about choking | 2.6 (1.29) | 2.47–2.81 | 52 (23.2) | 65 (29.0) | 39 (17.4) | 48 (21.4) | 20 (8.9) |
| 4. Embarrassed | 2.0 (1.14) | 1.90–2.20 | 95 (42.4) | 60 (26.8) | 40 (17.9) | 21 (9.4) | 8 (3.6) |
| 5. Worried about swallowing in public | 2.9 (1.27) | 2.77–3.10 | 39 (17.4) | 39 (17.4) | 73 (32.6) | 43 (19.2) | 30 (13.4) |
| 6. Difficulty in social activities | 2.3 (1.23) | 2.19–2.51 | 71 (31.7) | 60 (26.8) | 53 (23.7) | 24 (10.7) | 16 (7.1) |
| 7. Family relationships | 1.6 (1.01) | 1.46–1.73 | 151 (67.4) | 33 (14.7) | 26 (11.6) | 8 (3.6) | 6 (2.7) |
| 8. Friendships | 1.6 (1.01) | 1.50–1.77 | 141 (62.9) | 46 (20.5) | 20 (8.9) | 11 (4.9) | 6 (2.7) |
| 9. Keep up at work or school | 1.6 (1.15) | 1.47–1.78 | 112 (50.0) | 52 (23.2) | 18 (8.0) | 16 (7.1) | 6 (2.7) |
| 10. Miss work or school | 1.3 (0.99) | 1.17–1.43 | 149 (66.5) | 26 (11.6) | 14 (6.3) | 6 (2.7) | 5 (2.2) |
| 11. Disturbed sleep | 1.9 (1.07) | 1.77–2.06 | 106 (47.3) | 58 (25.9) | 38 (17.0) | 17 (7.6) | 5 (2.2) |
| Week 24 EoE-IQ score (n = 212) | |||||||
| 1. Bothered by symptoms | 2.2 (1.03) | 2.09–2.37 | 51 (24.1) | 95 (44.8) | 40 (18.9) | 18 (8.5) | 8 (3.8) |
| 2. Worried about swallowing | 2.0 (1.09) | 1.90–2.19 | 80 (37.7) | 75 (35.4) | 31 (14.6) | 19 (9.0) | 7 (3.3) |
| 3. Worried about choking | 1.8 (1.00) | 1.62–1.90 | 114 (53.8) | 55 (25.9) | 27 (12.7) | 12 (5.7) | 4 (1.9) |
| 4. Embarrassed | 1.4 (0.84) | 1.27–1.50 | 164 (77.4) | 28 (13.2) | 11 (5.2) | 5 (2.4) | 4 (1.9) |
| 5. Worried about swallowing in public | 1.8 (1.10) | 1.63–1.93 | 117 (55.2) | 54 (25.5) | 19 (9.0) | 14 (6.6) | 8 (3.8) |
| 6. Difficulty in social activities | 1.5 (0.94) | 1.39–1.65 | 148 (69.8) | 36 (17.0) | 12 (5.7) | 14 (6.6) | 2 (0.9) |
| 7. Family relationships | 1.2 (0.59) | 1.12–1.28 | 185 (87.3) | 13 (6.1) | 13 (6.1) | 0 (0.0) | 1 (0.5) |
| 8. Friendships | 1.2 (0.61) | 1.13–1.30 | 184 (86.8) | 15 (7.1) | 10 (4.7) | 2 (0.9) | 1 (0.5) |
| 9. Keep up at work or school | 1.2 (0.83) | 1.04–1.27 | 142 (67.0) | 27 (12.7) | 8 (3.8) | 5 (2.4) | 1 (0.5) |
| 10. Miss work or school | 1.1 (0.75) | 0.98–1.18 | 152 (71.7) | 17 (8.0) | 10 (4.7) | 2 (0.9) | 1 (0.5) |
| 11. Disturbed sleep | 1.5 (0.80) | 1.36–1.58 | 144 (67.9) | 46 (21.7) | 14 (6.6) | 7 (3.3) | 1 (0.5) |
CI, confidence interval; EoE-IQ, Eosinophilic Esophagitis Impact Questionnaire; SD, standard deviation