Table 2.

Sensitivity to MEN1611 of NSCLC with wild-type PI3KCA.

Cell line	IC50 MEN1611 (µM)
HCC827	1.74 ± 0.35
RA1	4.17 ± 0.49*
RA2	4.98 ± 0.48**
RB1	6.63 ± 0.53**
RB1.1	3.59 ± 0.16*
RB2	6.60 ± 1.92

MEN1611 IC₅₀ (µM) mean values ± SEM are representative of three independent experiments. In each experiment, R² was >0.9. Unpaired t-test was performed to evaluate differences in sample means.

NSCLC, non-small cell lung cancer.

*p < 0.05, **p < 0.01.