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Immunohistochemistry analysis of xenograft nodule sections.
| (A) % Ki67+ cells/nuclei | ||||
|---|---|---|---|---|
| Drug | HCC827 | RA1 | RB1 | RA2 |
| Vehicle | 32.6 ± 3.2 | 28.1 ± 4.2 | 25.4 ± 3.2 | 33.9 ± 3.2 |
| Gefitinib | 25.3 ± 6.5* | n.d. | 32.6 ± 8.9 | n.d. |
| MEN1611 | 24.7 ± 5.8* | 29.6 ± 8.4 | 28.5 ± 6.5 | 30.4 ± 5.5 |
| Gefitinib+MEN1611 | n.d. | n.d. | 37.1 ± 3.9** | n.d. |
