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. 2023 Nov 14;15:1277731. doi: 10.3389/fnagi.2023.1277731

Table 4.

Information on 15 SNPs identified in cross-sectional XWAS and longitudinal XWAS.

XWAS SNP Position Allele MAF p-value of HWE test Gene
Major Minor
Cross-sectional rs5927116 32,974,359 C T 0.450 0.593 DMD
rs4596772 79,847,546 G A 0.377 0.211 Near to TBX22
rs5929538 113,049,595 G A 0.485 0.485 LOC101928437
rs2213488a 125,142,940 C T 0.255 0.208 TENM1
rs5920524 145,431,897 C T 0.500 0.996 Near to SPANXN1
rs5945306 153,412,601 T C 0.198 0.392 ZFP92
Longitudinal rs12157031 20,663,243 C T 0.072 0.606 LOC124905257
rs428303 97,936,863 G A 0.365 0.014 Near to NCKAP1P1
rs4829868 137,246,548 G T 0.085 0.116 Near to RAC1P4
rs5931111 137,258,892 C T 0.091 3.112 × 10−4 Near to RAC1P4
rs5953487 140,548,099 T C 0.333 0.014 Near to LOC105373344
rs10284107 143,202,859 A G 0.226 0.747 Near to RN7SKP149
rs5955016 143,402,732 T C 0.430 0.789 Near to MTND1P33
rs6540385 148,580,366 T C 0.428 0.090 AFF2
rs763320 148,593,511 T G 0.433 0.134 AFF2

HWE, Hardy–Weinberg equilibrium; MAF, minor allele frequency. aFor SNP rs2213488, the estimation of the MAF and the calculation of the p-value of the HWE test were based on ADNI cohort GO/2 with 792 subjects.