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. 2023 Nov 13;25:e49939. doi: 10.2196/49939

Table 3.

Effects of the mobile app for gynecologic cancer support program on primary and secondary health outcomes at 12 weeks (T1) and 24 weeks (T2) with intention-to-treat analysis (N=168)a.

Intervention effect Intervention group (n=84), mean (SD/SE) Control group (n=84), mean (SD/SE) Mean difference (95% CI) P value Effect size (Cohen d)b
Primary outcomes

Mishel Uncertainty in Illness Scale for Adults


T1 (unadjusted) 63.04 (11.43) 64.30 (13.93) –1.26 (–5.02 to 2.50) .51 –0.10


T1 (adjusted) 62.74 (1.23) 64.60 (1.23) –1.86 (–5.29 to 1.57) .29 –0.15


T2 (unadjusted) 56.87 (13.20) 64.07 (12.47) –7.20 (–11.20 to –3.20) .001 –0.56


T2 (adjusted) 56.63 (1.30) 64.32 (1.30) –7.69 (–11.31 to –4.07) <.001 –0.60
Secondary outcomes

Functional Assessment of Cancer Therapy-General


T1 (unadjusted) 70.52 (16.05) 69.78 (17.02) 0.74 (–4.47 to 5.96) .78 0.04


T1 (adjusted) 70.67 (1.54) 69.63 (1.54) 1.05 (–3.25 to 5.34) .63 0.06


T2 (unadjusted) 75.47 (15.50) 70.89 (16.73) 4.58 (–0.85 to 10.01) .10 0.28


T2 (adjusted) 75.57 (1.66) 70.80 (1.66) 4.77 (0.12 to 9.41) .04 0.30

MD Anderson Symptom Inventory


T1 (unadjusted) 2.96 (1.74) 3.09 (1.76) –0.13 (–0.67 to 0.42) .65 –0.07


T1 (adjusted) 2.93 (0.16) 3.12 (0.16) –0.19 (–0.64 to 0.26) .41 –0.11


T2 (unadjusted) 2.23 (1.62) 2.46 (1.88) –0.23 (–0.81 to 0.35) .43 –0.13


T2 (adjusted) 2.21 (0.18) 2.49 (0.18) –0.28 (–0.77 to 0.21) .26 –0.16

Multidimensional Scale of Perceived Social Support


T1 (unadjusted) 5.18 (0.95) 5.44 (0.82) –0.26 (–0.53 to 0.02) .06 –0.29


T1 (adjusted) 5.21 (0.09) 5.41 (0.09) –0.19 (–0.44 to 0.05) .12 –0.23


T2 (unadjusted) 5.22 (0.88) 5.41 (0.83) –0.20 (–0.48 to 0.09) .18 –0.22


T2 (adjusted) 5.25 (0.09) 5.39 (0.09) –0.14 (–0.39 to 0.10) .25 –0.16

aRepeated measures multivariate analysis of covariance was used to examine the efficacy of the mobile app for gynecologic cancer support program on primary and secondary health outcomes at 12 weeks (T1) and 24 weeks (T2), adjusted by baseline corresponding health outcomes.

bAdjusted effect sizes were calculated by dividing the between-group difference of the postintervention means (adjusted for baseline values) by the pooled standard deviation [41].