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. 2023 Nov 28;2023(11):CD012152. doi: 10.1002/14651858.CD012152.pub4

TCTR20190805003.

Methods Randomised double‐blind, placebo‐controlled trial
Participants 600 infants
Inclusion criteria: late preterm (34 to 37 weeks' gestation), small (< 10th centile) or large‐for‐gestational age (> 90th centile), infants of diabetic mothers, low birthweight (< 2500 g) or macrosomia (> 4000 g)
Exclusion criteria: received oral feed or intravenous treatment for hypoglycaemia, congenital abnormality, admission to NICU, birthweight < 1800 grams
Setting: Thailand
Interventions 40% dextrose gel (0.5 ml/L) applied into the buccal mucosa within 48 hours after birth
vs
Arboxymethyl cellulose placebo gel massaged into the buccal mucosa using the same protocol as the intervention
Outcomes Primary outcome
  • Admission to special care nursery due to treatment failure (within 30 minutes after intervention)


Secondary outcomes
  • Length of hospital stay

Notes Trial registration: TCTR20190805003. Trial completed but unpublished ‐ authors contacted in May 2023 for additional information

BMI: body mass index
DCT: Direct Coombs Test
NICU: neonatal intensive care unit
Rh: rhesus
vs: versus