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. 2023 Nov 28;25:228. doi: 10.1186/s13075-023-03195-4

Table 2.

Therapies applied at inclusion in the registry and at 4-year follow-up

At baseline
N = 400
After 4 years
N = 81 (all patients)
Any medication 387 (96.8%) 59 (72.8%) p < 0.001
NSAIDs 344 (86%) 32 (39.5%) p < 0.001
Systemic glucocorticoids, total 46 (11.5%) 3 (3.7%) p = 0.003
 < 0.2 mg per kg BW 21 (5.3) 2 (2.5%) p = 0.285
  ≥ 0.2 mg per kg BW 33 (8.3%) 2 (2.5%) p = 0.068
Bisphosphonates 34 (8.5%) 3 (3.7%) p = 0.140
DMARDs, totala 56 (16.4%) 21 (28.4%) p = 0.008
csDMARDs 43 (12.6%) 13 (17.6%) p = 0.129
 Methotrexate 30 (8.8%) 10 (13.5%) p = 0.21
 Sulfasalazine 13 (3.8%) 3 (4.1%) p = 0.836
bDMARD 21 (6.1%) 9 (12.2%) p = 0.003
 Etanercept 10 (2.9%) 3 (4.1%) p = 0.542
 Adalimumab 11 (3.2%) 6 (8.1%) p = 0.05

NSAIDs non-steroidal anti-rheumatic drugs, csDMARDs conventional synthetic disease-modifying anti-rheumatic drugs, bDMARDs biological DMARDs, BW body weight

aInformation on DMARD therapy was available for 341 patients at baseline and 74 patients at 4-year follow-up, respectively