Table 3.
Relationship Between Serum Lipid-Lipoprotein Levels and ApoE Phenotype in DN Patients and Controls
| Variable | ε2 (E2/E2 + E2/E3) | ε3 (E3/E3) | ε4 (E3/E4 + E4/E4) | |||
|---|---|---|---|---|---|---|
| Control (N = 36) | DN (N = 63) | Control (N = 362) | DN (N = 193) | Control (N = 77) | DN (N = 42) | |
| HbA1c (%) | 10.31 ± 2.72 | 10.27 ± 2.70 | 10.60 ± 2.76 | 10.54 ± 2.63 | 10.38 ± 2.67 | 10.39 ± 2.42 |
| UTP (g/24h) | 0.33 ± 0.21 | 1.13 ± 1.11*** | 0.27 ± 0.21 | 1.32 ± 1.23*** | 0.24 ± 0.16 | 0.76 ± 0.58*** |
| TG (mmol/L) | 1.11 ± 0.37 | 2.14 ± 1.54*** | 1.73 ± 1.00 | 2.07 ± 1.51** | 1.84 ± 1.11 | 1.69 ± 1.30 |
| TC (mmol/L) | 4.35 ± 1.09 | 4.78 ± 1.50 | 4.92 ± 1.13 | 4.96 ± 1.35 | 4.83 ± 1.00 | 4.38 ± 1.18 |
| LDL-C (mmol/L) | 2.26 ± 0.88 | 2.57 ± 0.92 | 2.81 ± 0.79 | 2.83 ± 0.88 | 2.81 ± 0.75 | 2.54 ± 0.81 |
| HDL-C (mmol/L) | 1.40 ± 0.32 | 1.13 ± 0.33*** | 1.22 ± 0.31 | 1.18 ± 0.40 | 1.18 ± 0.36 | 1.09 ± 0.33 |
Notes: **p<0.01, ***p<0.001: Comparison with Control in the same allele group.
Abbreviations: HbA1c, glycated hemoglobin; UTP, 24-hour urinary protein quantity; TG, triglyceride; TC, total cholesterol; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol.