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. 2023 Nov 3;72(4):1–21. doi: 10.15585/mmwr.rr7204a1

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Figure is a flow chart illustrating the primary algorithm for hepatitis C virus testing of perinatally exposed children in the United States in 2023. — Algorithm for hepatitis C virus testing of perinatally exposed children — United States, 2023*^,†,§,¶

Abbreviations: FDA = Food and Drug Administration; HCV = hepatitis C virus; NAT = nucleic acid test.

* Perinatally exposed children are children born to pregnant persons with HCV infection.

^† Perinatally exposed children aged 7–17 months who have not previously been tested also should receive a NAT for HCV RNA.

^§ Off-label use of an FDA-approved diagnostic test requires validation by the testing laboratory.

^¶ No further follow-up needed after a negative HCV RNA performed at age 2–6 months unless clinically warranted (i.e., clinical symptoms or signs or laboratory findings consistent with hepatitis C).