Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Potential molecular mechanisms of antifungal drug resistance
| Alterations in drug import |
| Alterations in intracellular drug processing |
| Modification |
| Degradation |
| Alterations in the target enzyme |
| Point mutations |
| Overexpression |
| Gene amplification |
| Gene conversion or mitotic recombination |
| Alterations in other enzymes in the ergosterol biosynthetic pathway |
| Alterations in efflux pumps |
| ABC transporters |
| Major facilitators |
