Skip to main content
. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: Regen Eng Transl Med. 2023 Jan 26;9(3):424–430. doi: 10.1007/s40883-022-00292-9

Figure 1.

Figure 1.

In vivo iPN hydrogel injection with and without PLGA-encapsulated dye. (a) Adult rats were injected subcutaneously with two 150 μL iPN hydrogel or saline solutions containing free dye or PLGA-encapsulated dye. Example ROIs are shown in the circles and represent the area measured for radiant efficiency (correlated to amount of signal). (b) Short-term release profile: images were captured 10 × 3 minutes (0–27 minutes). There was a statistically significant difference in signal beginning at 18 minutes post-injection. (c) Long-term release profile: images were obtained over the course of 72 hours. Statistical differences appeared at 24 hours post-injection between the iPN groups, *p-value<0.05 for iPN with PLGA-encapsulated dye versus iPN with free dye.