TABLE 3.
Eradication rate accessed by a negative stool test according to characteristics of 139 children treated for Helicobacter pylori (H. pylori) infection
| Characteristics | N | Success % | OR | P | aOR | P |
|---|---|---|---|---|---|---|
| Age (years) | 0.09 | 0.09 | ||||
| <11 | 97 | 60.8 | 1 | 1 | ||
| ≥11 | 42 | 45.2 | 0.53 (0.26–1.11) | 0.41 (0.15–1.14) | ||
| Gender | 0.02 | 0.02 | ||||
| Boys | 70 | 65.7 | 2.22 (1.12–4.39) | 3.04 (1.20–7.73) | ||
| Girls | 69 | 46.4 | 1 | 1 | ||
| Living area | 0.59 | 0.71 | ||||
| Provinces | 58 | 53.5 | 1 | 1 | ||
| Ho Chi Minh City | 81 | 58.0 | 1.20 (0.61–2.37) | 1.18 (0.49–2.83) | ||
| + Rural | 49 | 53.1 | 1 | |||
| + Urban | 32 | 65.6 | 1.69 (0.67–4.24) | 0.26 | ||
| History of pretreatment* | 0.69 | 0.22 | ||||
| Yes | 32 | 59.4 | 1.18 (0.53–2.64) | 2.00 (0.67–5.92) | ||
| No | 103 | 55.3 | 1 | 1 | ||
| Malnutrition | 0.01 | 0.03 | ||||
| Yes | 22 | 31.8 | 0.30 (0.11–0.80) | 0.27 (0.08–0.87) | ||
| No | 117 | 60.7 | 1 | 1 | ||
| Endoscopic findings | 0.52 | 0.74 | ||||
| Ulcers | 35 | 51.4 | 0.78 (0.36–1.67) | 1.19 (0.44–3.23) | ||
| Gastritis | 104 | 57.7 | 1 | 1 | ||
| cagA status† | 0.01 | 0.02 | ||||
| Positive | 101 | 49.5 | 0.36 (0.16–0.83) | 0.25 (0.08–0.78) | ||
| Negative | 37 | 73.0 | 1 | 1 | ||
| vacA genotypes† | 0.73 | 0.69 | ||||
| s1/m1 | 44 | 54.6 | 0.60 (0.10–3.62) | 0.70 (0.09–5.51) | ||
| s1/m2 | 56 | 58.9 | 0.72 (0.12–4.25) | 0.35 (0.04–2.94) | ||
| s2/m2 | 1 | 100 | 1 | 1 | ||
| Mixed infections | 31 | 48.4 | 0.47 (0.07–2.94) | 0.46 (0.06–3.62) | ||
| Incomplete vacA | 6 | 66.7 | ||||
| Antibiotic susceptibility to regimens‡ | 0.61 | |||||
| Susceptible to 2 ATB | 38 | 55.3 | 1 | |||
| Resistance to 1 ATB | 16 | 68.8 | 1.78 (0.52–6.13) | |||
| Resistance to 2 ATB | 4 | 50.0 | 0.81 (0.10–6.36) | |||
| Side effects§ | 0.66 | 0.99 | ||||
| Yes | 19 | 63.2 | 1.26 (0.45–3.46) | 0.99 (0.32–3.10) | ||
| No | 97 | 57.7 | 1 | 1 | ||
| Compliance with treatment∥ | 0.89 | 0.65 | ||||
| Yes | 96 | 58.3 | 1.07 (0.40–2.86) | 1.32 (0.40–4.29) | ||
| No | 20 | 60.0 | 1 | 1 |
aOR = adjusted odds ratio; ATB = antibiotics; OR, odds ratio.
*Four missing data.
†One missing data.
‡Antimicrobial susceptibility testing results were available in 58 patients.
§Information on side effects was available on 115 patients.
∥Information on compliance with treatment was available on 116 patients.