Table 5.

Type of non-invasive ventilation (NIV) used amongst congenital myasthenic syndrome (CMS) patients with a history of NIV use (n = 15)

ID	CMS subtype	Type of ventilation	Further information
35	CHAT	Nocturnal	Intermittent use of nocturnal NIV via tracheostomy commenced at 10 months and continued up to the point of discharge aged 17
15	CHRNG	Nocturnal	Continuous nocturnal and diurnal NIV via a facemask from birth until aged 3 months. Switched to nocturnal NIV that was poorly tolerated. Aged 3 years moved to nightly Optiflow
9	COLQ	Nocturnal	Diurnal and nocturnal NIV for ∼20 hours per day from birth-1 years old. Reducing regimen every two weeks by age 2. Currently on nocturnal NIV
32	COLQ	Nocturnal and diurnal	Nocturnal NIV from 11 to 14 years old, with 2 hours of diurnal NIV
36	COLQ	Nocturnal	Continued nocturnal NIV use commenced at 11 years up to at the point of discharge aged 19
16	DOK7	Nocturnal	Nocturnal NIV regime commenced at 6 months of age and discontinued at 3 years
17	DOK7	Nocturnal	Nocturnal NIV commenced at age 15
18	DOK7	Nocturnal	Commenced nocturnal and diurnal ventilation via tracheostomy age 1, with regimen altered to solely nocturnal ventilation via tracheostomy aged 2
33	DOK7	Nocturnal	Nocturnal ventilation commenced at age 17
19	CHRNE FCS	Emergency non-invasive ventilation	Moved to emergency NIV availability after diurnal NIV regime aged 3 to 8 years
26	RAPSN	Emergency non-invasive ventilation	Moved to emergency NIV availability after diurnal NIV regime from 6 to 7 years
29	RAPSN	Emergency non-invasive ventilation	Moved to emergency NIV availability after poor tolerance of nocturnal NIV aged 16
34	RAPSN	Nocturnal	Nocturnal NIV commenced aged 16, and continued nocturnal NIV use at the point of discharge aged 18
39	RAPSN	Nocturnal	Nocturnal NIV from birth

Summary of ventilation history after a review of patient records included.