. 2023 Aug 9;36(6):1391–1404. doi: 10.1007/s10534-023-00525-6

Table 4.

Effect of myco-fabricated ZnO-NPs on changes in acetylcholinesterase, acetylcholine, dopamine, and serotonin in the brain of mice induced by AlCl₃

Parameters	Groups						F value	p value
Parameters	G1	G2	G3	G4	G5	G6	F value	p value
AchE (pg/mg)	0.36 ± 0.04^d	1.91 ± 0.14^a	0.39 ± 0.02^d	0.38 ± 0.03^d	0.53 ± 0.02^c	0.62 ± 0.04^b	436.08	≤ 0.001
% of changes		430.56	8.33	5.56	47.22	72.22
Ach (pg/mg)	6.0 ± 0.36^a	0.91 ± 0.14^d	6.34 ± 0.21^a	5.76 ± 0.32^a	5.0 ± 0.16^b	4.46 ± 0.29^c	288.9	≤ 0.001
% of changes		−84.83	5.67	−4	−16.67	−25.67
Dopamine (ng/mg)	33.46 ± 2.72^a	12.4 ± 0.52^c	35.0 ± 1.19^a	33.6 ± 0.37^a	34.12 ± 3.69^a	21.76 ± 0.97^b	107.94	≤ 0.001
% of changes		−62.94	4.60	0.42	1.97	−34.96
Serotonin (ng/mg)	116.76 ± 4.64^a	49.02 ± 2.35^c	105.7 ± 7.11^a	96.0 ± 3.54^ab	93.0 ± 5.09^ab	69.66 ± 5.38^bc	121.06	≤ 0.001
% of changes		−58.02	−9.47	−17.78	−20.35	−40.34

The mean and standard deviation of ten mice from each group are used to represent the values. Means with different superscripts within the same row differ significantly at (p ≤ 0.05)