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. 2023 Nov 28;13:20975. doi: 10.1038/s41598-023-48295-y

Table 2.

Clinical Characteristics of Propensity Score-matched Pairs of Subjects in Protocol 2.

Variables Control (n = 18) Nonfunctioning adrenal adenomas (n = 18) P value
Age, year 65 ± 14 65 ± 10 0.92
Sex, men/women 13/5 14/4 0.70
Body mass index, kg/m2 26.1 ± 4.7 25.8 ± 2.6 0.85
Systolic blood pressure, mmHg 137 ± 15 134 ± 15 0.56
Diastolic blood pressure, mmHg 83 ± 12 79 ± 11 0.37
Heart rate, bpm 71 ± 12 74 ± 12 0.55
Total cholesterol, mmol/L 4.60 ± 1.09 4.84 ± 0.72 0.47
Triglycerides, mmol/L 1.75 ± 1.52 1.93 ± 1.61 0.76
High-density lipoprotein cholesterol, mmol/L 1.42 ± 0.52 1.32 ± 0.49 0.57
Low-density lipoprotein cholesterol, mmol/L 2.64 ± 0.83 2.84 ± 0.62 0.41
Glucose, mmol/L 6.94 ± 1.61 6.11 ± 1.11 0.09
Hemoglobin A1c, % 6.2 ± 0.9 5.9 ± 0.8 0.44
Blood urea nitrogen, mmol/L 5.00 ± 1.43 5.36 ± 1.79 0.43
Creatinine, μmol/L 63.65 ± 13.26 76.02 ± 13.26 0.07
Current smoker, n (%) 1 (5.6) 3 (16.7) 0.28
Medical history, n (%)
 Hypertension 15 (83.3) 15 (83.3) 1.00
 Dyslipidemia 11 (61.1) 11 (61.1) 1.00
 Diabetes mellitus 4 (22.2) 4 (22.2) 1.00
 Previous coronary heart disease 0 (0.0) 0 (0.0) N/A
 Previous stroke 1 (5.6) 3 (16.7) 0.28
Medication, n (%)
 Calcium channel blockers 11 (61.1) 8 (44.4) 0.32
 Angiotensin-converting enzyme inhibitors 0 (0.0) 0 (0.0) 1.00
 Angiotensin II receptor blockers 3 (16.7) 6 (33.3) 0.24
 Mineralocorticoid receptor blockers 0 (0.0) 0 (0.0) N/A
 Beta-blockers 3 (16.7) 1 (5.6) 0.28
 Alpha-blockers 0 (0.0) 1 (5.6) 0.23
 Statins 6 (27.8) 5 (27.8) 0.72
 Nitrates 0 (0.0) 0 (0.0) N/A
Medically treated diabetes mellitus
 Any 2 (11.1) 1 (5.6) 0.54
 Insulin-dependent 0 (0.0) 0 (0.0) N/A
Flow-mediated vasodilation, % 3.4 ± 2.4 2.4 ± 1.9 0.19
Nitroglycerine-induced vasodilation, % 13.6 ± 4.6 12.1 ± 4.2 0.35

N/A indicates not applicable.

Results are presented as means ± SD for continuous variables and percentages for categorical variables.