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. 2023 Nov 28;13:20974. doi: 10.1038/s41598-023-48260-9

Table 2.

Comparisons between American Indian/Alaska Native and Non-Hispanic White adult inpatients from the CEC-UW COVID-19 cohort on comorbid disorders, treatment access, and area deprivation.

Characteristic American Indian/
Alaska Native
N = 546
Non-Hispanic White p valueb
Full sample
N = 78,128
p valuea Matched sampled
N = 2,645
N % N % N %
Sex 0.698 0.948
 Female 270 49.5 37,984 48.6 1299 49.1
 Male 276 50.5 40,412 51.4 1346 50.9
Age < 0.001 0.833
 18–49 188 34.4 14,647 18.7 874 33.0
 50–64 164 30.0 19,737 25.3 805 30.4
 65+ 194 35.5 43,744 56.0 966 36.5
Smoking status 0.038 0.95
 Never smoker 288 52.7 38,441 49.2 1402 53.0
 Former smoker 178 32.6 28,989 37.1 877 33.2
 Current smoker 55 10.1 6252 8.0 256 6.7
 Missing 25 4.6 4446 5.7 110 4.2
Current comorbidities
 Obesity 159 29.1 19,337 24.8 0.018 695 26.3 0.184
 Diabetes (Type 2) 224 41.0 21,449 27.5 < 0.001 640 24.2 < 0.001
 Chronic renal failure 113 20.7 15,669 20.1 0.231 444 16.8 0.026
 Liver disease 64 11.7 4807 6.2 < 0.001 173 6.5 < 0.001
 Heart disease 331 60.6 50,853 65.1 0.029 1493 56.5 0.070
 Cancer 41 7.5 6690 8.6 0.380 207 7.8 0.818
 Alcohol use disorder 39 7.1 2416 3.1 < 0.001 104 3.3 0.001
 Drug use disorder 27 4.9 2245 2.9 0.004 110 4.2 0.399
Insurance type < 0.001 < 0.001
 Commercial 142 26.0 21,190 27.1 1014 38.3
 Medicare 251 46.0 46,960 60.1 1172 44.3
 Medicaid 98 17.9 4677 6.0 261 9.9
 Uninsured 20 3.7 1289 1.6 51 1.9
 Other 35 6.4 4012 5.1 147 5.7
Received antiviral medication  0.880  0.498
 No 270 49.6 39,042 50.0 1355 51.2
 Yes 274 50.4 39,086 50.0 1290 48.8
Distance to treatment < 0.001 < 0.001
 < 60 miles 420 76.9 73,246 93.8 2589 90.3
 ≥ 60 miles 126 23.1 7898 6.2 256 9.7
Region < 0.001 0.860
 Northeast 109 20.0 26,714 34.2 540 20.4
 Midwest 145 26.6 27,102 34.7 725 27.4
 South 132 24.2 20,367 26.1 660 25.0
 West 160 29.3 3909 5.0 720 27.2
Urbanicity < 0.001 < 0.001
 Urban 472 86.4 72,727 93.1 2465 93.2
 Rural 74 13.6 5360 6.9 180 6.8
Area social deprivation quintile < 0.001 < 0.001
 Lowest 20% 38 7.1 15,328 19.8 518 19.9
 20–40% 48 9.0 15,602 20.1 459 17.7
 40–60% 96 17.9 15,586 20.1 522 20.1
 60–80% 94 17.6 15,471 20.0 525 20.2
Highest 20% 259 48.4 15,514 20.0 576 22.2
Year 0.062 0.530
 Feb 2020–Dec 2020 231 42.3 30,007 38.4 1075 40.6
 Jan 2021–Jan 2022 315 57.7 48,121 61.6 1570 59.4
Fully vaccinatedc 181 33.2 30,265 38.7 0.026 993 37.5 0.663
 No 479 88.1 66,140 84.7 2311 87.4
 Yes 65 11.9 11,988 15.3 334 12.6

aChi-square tests comparing proportions to AIAN.

bCochran–Mantel–Haenszel tests comparing proportions to AIAN.

cFully vaccinated before hospitalization; see Supplemental Text S2.

dMatch 1 sample used for matched analyses; samples were matched on sex, age, region, and year.