Table 4.
Overview imaging analysis.
Area | BA | HEM | MNI | Voxel | t | p | COI | |
---|---|---|---|---|---|---|---|---|
Bromocriptine > Placebo. Contrasts between treatment groups show higher activation in bromocriptine compared to the placebo group in extinction-related brain areas during acquisition, extinction, and recall of extinction memory. [Two-sample test, FWE-corrected p < 0.05, k = 10, on cluster level] | ||||||||
Extinction | ||||||||
AAA Extinction | Superior frontal gyrus | 9/10 | R | 16 52 30 | 227 | 4.10 | 0.04 | Fixations |
Recall | ||||||||
AAA Extinction | Paracentral Lobule | 6 | R | 28 6 − 12 | 129 | 4.23 | 0.05 | Fixations |
ABA Extinction | Insula | 13 | R | 28 − 18 14 | 92 | 4.95 | 0.01 | Dwell |
Bromocriptine < Placebo. Contrasts between treatment groups show higher activation in placebo compared to the bromocriptine group in extinction-related brain areas during acquisition, extinction, and recall of extinction memory. [Two-sample test, FWE-corrected p < 0.05, k = 10, on cluster level] | ||||||||
Extinction | ||||||||
ABA Retrieval | Inferior Frontal Gyrus | 46 | L | − 40 34 20 | 104 | 5.84 | 0.001 | Fixations |
Inferior Frontal Gyrus | 46 | L | − 40 34 20 | 117 | 6.20 | < 0.001 | Dwell | |
Recall | ||||||||
AAA Retrieval | Inferior Frontal Gyrus | 45/46 | R | 42 18 34 | 51 | 4.19 | 0.012 | Dwell |
Overview of a positive correlation between BOLD activation of all participants and learning errors, fixations, and dwell as a covariate of interest (COI) [One-sample test, FWE-corrected p < 0.05, k = 10, on cluster level; *SVC peak level] | ||||||||
Extinction | ||||||||
ABA Extinction | Inferior Frontal Gyrus | 47 | L | − 28 22 18 | 108 | 5.12 | 0.024 | Fixations |
Recall | ||||||||
AAA Extinction | Parahippocampal Gyrus* | 28 | L | − 20 −12 −24 | 65 | 4.46 | 0.024 | Fixations |
ABA Retrieval | Insula | 13 | R | − 34 − 26 10 | 118 | 5.04 | 0.01 | Fixations |
Hippocampus | 22 | R | 35 − 12 − 4 | 124 | 5.91 | 0.00 | Dwell | |
Negative correlation between BOLD activation of all participants and dwell as a covariate of interest (COI) [One-sample test, FWE-corrected p < 0.05, k = 10, on cluster level] | ||||||||
Extinction | ||||||||
AAA Retrieval | Anterior Cingulate Cortex | 32 | L | − 14 42 6 | 116 | 4.83 | 0.05 | Dwell |