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. 2023 Nov 28;14:7799. doi: 10.1038/s41467-023-43372-2

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — Redistributed patients from one severity category to another between different grading systems are compared to the remaining patients in the original category. a Kaplan–Meier OS curves with 95% CI of redistributed patients from MAGIC grade III to PC1-grade ≤II (light green) compared to intersection grade III patients in both grades (dark green). Strata are compared with the two-sided log-rank test. The phenotypes are detailed in Supplementary Data 8. b Comparison of Kaplan-Meier OS curves with 95% CI of redistributed patients from Consensus grade III to PC1-grade ≤ II (light green) to intersection of grade III patients in both consensus and PC1 (dark-green). Strata are compared with the two-sided log-rank test. c Kaplan–Meier OS curves with 95% CI of redistributed patients from MAGIC grade III to PC1-grade I (light green) and PC1-grade II (green) are compared to grade III patients in both MAGIC and PC1 (blue-green). d Kaplan–Meier OS curves with 95% CI of redistributed patients from Consensus grade III to PC1-grade I (light green), to PC1-grade II (green) are compared to the intersection of grade III patients (blue-green). e Cumulative incidence curves of NRM are compared for the same strata as in c. Error bands show 95% CI. f Cumulative incidence curves of NRM are compared for redistributed Consensus grade III patients to PC1 including PC1-grade IV (dark blue). Error bands show 95% CI. Strata for NRM are compared with the two-sided Gray test.