. 2023 Sep 12;51(1):245–257. doi: 10.1007/s00259-023-06416-9

Table 2.

Reproducibility coefficient (RDC*) grades for reproducibility

Grade	Upper value of 95% CI for RDC*	Segmentation	Administered activity	Whole liver volume	Whole liver absorbed dose	Whole liver normal tissue volume	Whole liver NTAD	Perfused normal tissue volume	Perfused NTAD	Total perfused tumour volume	Total perfused TAD
1	< 1.5	Anatomic	X	X	X
1	< 1.5	^99mTc-MAA SPECT
2	≥ 1.5 and < 2	Anatomic				X
2	≥ 1.5 and < 2	^99mTc-MAA SPECT		X		X
3	≥ 2 and < 3	Anatomic					X	X	X		X
3	≥ 2 and < 3	^99mTc-MAA SPECT			X				X
4	≥ 3	Anatomic								X
4	≥ 3	^99mTc-MAA SPECT	X				X	X		X	X

CI, confidence interval; RDC, reproducibility coefficient; ^99mTc-MAA, technetium-99m macroaggregated albumin; NTAD, normal tissue absorbed dose; SPECT, single-photon emission computed tomography; TAD, tumour absorbed dose

^*Corresponding to the maximum fold difference in the measurement from two different reviewers in 95% of cases