Table 3.
Intra-observer variability (IOV) (see Supplementary information for definition)
| 99mTc-MAA SPECT segmentation, n = 160a | Anatomic segmentation, n = 160a | |
|---|---|---|
| Administered activity (GBq) | 0.6 | 0.3 |
| Whole liver volume (cm3) | 142.5 | 107.8 |
| Whole liver absorbed dose (Gy) | 10.7 | 8.0 |
| Perfused liver volume (cm3) | 236.1 | 133.5 |
| Total perfused tumours volume (cm3) | 153.3 | 226.2 |
| Total perfused tumours absorbed dose (Gy) | 121.4 | 50.8 |
| Perfused normal tissue volume (cm3) | 231.4 | 268.6 |
| Perfused normal tissue absorbed dose (Gy) | 19.7 | 16.7 |
| Target lesion volume (cm3) | 146.2 | 226.8 |
| Target lesion absorbed dose (Gy) | 122.3 | 58.8 |
99mTc-MAA, technetium-99 macroaggregated albumin; SPECT, single-photon emission computed tomography
an = 160 (i.e., 10 patients × 8 reviewers × 2 assessments); n = 136 for target lesion volume and target lesion absorbed dose