Table 1.

Blood parameters in Hbb^th3/+ vs Foxo3^−/−/Hbb^th3/+

Parameters	WT	Foxo3−/−	Hbbth3/+	Foxo3−/−/Hbbth3/+
RBC (109/L)	10 400 ± 300	9000 ± 100∗	6700 ± 700∗	7500 ± 600†
HGB (g/dL)	15.0 ± 0.3	14.8 ± 0.1	8.2 ± 0.3∗	9.2 ± 0.7†
HCT (%)	54.6 ± 1.6	52.8 ± 0.9	29.3 ± 5.2∗	34.5 ± 3.9†
MCV (fL)	52.8 ± 1.2	58.5 ± 0.8∗	41.2 ± 1.4∗	45.1 ± 3.0†
MCH (pg)	14.6 ± 0.2	16.4 ± 0.2	12.7 ± 1.6∗	12.5 ± 0.4
MCHC (g/dL)	27.4 ± 0.5	28.0 ± 0.3	30.2 ± 4.1	27.2 ± 1.4†
Retic (%)	3.6 ± 0.3	6.6 ± 0.5∗	24.0 ± 5.7∗	28.3 ± 7.0
n (mice)	9	10	7	10

HCT, hematocrit; HGB, hemoglobin; MCH, mean corpuscular hemoglobin; MCHC, MCH concentration; MCV, mean corpuscular volume; Retic, reticulocytes.

^∗P < .05 between WT and Foxo3^−/− or Hbb^th3/+.

^†P < .05 between Hbb^th3/+ and Foxo3^−/−/Hbb^th3/+.